Adolescent; Brain Neoplasms

Diagnosing relapse in children's brain tumors using metabolite profiles.

Malignant brain tumors in children generally have a very poor prognosis when they relapse and improvements are required in their management. It can be difficult to accurately diagnose abnormalities detected during tumor surveillance, and new …

Accurate classification of childhood brain tumours by in vivo ¹H MRS - a multi-centre study.

To evaluate the accuracy of single-voxel Magnetic Resonance Spectroscopy ((1)H MRS) as a non-invasive diagnostic aid for paediatric brain tumours in a multi-national study. Our hypotheses are (1) that automated classification based on (1)H MRS …

Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours.

Brain tumours cause the highest mortality and morbidity rate of all childhood tumour groups and new methods are required to improve clinical management. (1)H magnetic resonance spectroscopy (MRS) allows non-invasive concentration measurements of …