Biomarkers

A quantitative comparison of metabolite signals as detected by in vivo MRS with ex vivo 1H HR-MAS for childhood brain tumours.

(1)H MRS provides a powerful method for investigating tumour metabolism by allowing the measurement of metabolites in vivo. Recently, the technique of (1)H high-resolution magic angle spinning (HR-MAS) has been shown to produce high-quality data, …

Identification and characterisation of childhood cerebellar tumours by in vivo proton MRS.

(1)H MRS has great potential for the clinical investigation of childhood brain tumours, but the low incidence in, and difficulties of performing trials on, children have hampered progress in this area. Most studies have used a long-TE, thus limiting …